Virgo presented data at UEGW 2025 showing that EndoDINO was capable of predicting placebo responders from baseline colonoscopy videos. If the UNIFI trial had incorporated this in its trial design, the trial could have reached the same readout faster and at lower cost.

01

Placebo response

Control for placebo variability. Reduce trial size and increase statistical powering.
02

Subgroup response

Precision enrichment: identify likely responders from AI analysis of baseline endoscopy.
03

Bayesian priors

Generate powerful real-world data priors using EndoDINO at population scale.
04

Continuous AI scores

UC and CD endoscopic healing assessment beyond ordinal Mayo and SES-CD categories.

The data moat

Endoscopy video is the substrate. We capture more of it, from more procedures, than anyone else. The archive grows every day.

Capture is the foundation of everything downstream. Real-world endoscopy video (at population scale, longitudinal, and continuously growing) is what makes a foundation model for GI possible. Models built on smaller datasets plateau. Ours compound.

3M+ Procedures recorded across partner sites through 2025
1M+ New procedures captured each year, and growing
3.5B Video frames already in the EndoDINO training set
24/7 Live capture pipeline across institutional partners

The platform

One model base. Built for the full procedure.

Foundation model

EndoDINO

Virgo's foundation model for endoscopy. One model base for scoring, prediction, detection, and biomarker work, trained on the full procedure, not just the frame.

Build environment

EndoML

The environment for building on top of EndoDINO. A GI-specific model layer for clinical and research workflows.

Request access

See the full evidence package.

Manuscript, UEGW 2025 poster, benchmark results, and partnership models. Sent directly to qualified researchers and partners.

Infrastructure for the future of endoscopy AI.

Contact research Read the platform overview

Virgo builds frontier AI models to solve gut-mediated diseases colorectal cancer.

Press & podcast coverage

The most powerful AI for endoscopy. Trained on the largest dataset.

Largest endoscopy video dataset in the literature

57× more frames than the next largest dataset

Many of the most impactful human diseases are mediated by the gut.

State-of-the-art on GI benchmarks. Validated across sites, scopes, and patient populations.

State-of-the-art with frozen features

Predicting 8-week endoscopic healing from baseline video

State-of-the-art with frozen features.

From raw procedure video to a shared representation layer for GI.

Video Capture

Frame Extraction

Self-Supervised Learning

AI Representation

AI clinical trial design and measurement.

Placebo response

Subgroup response

Bayesian priors

Continuous AI scores

Endoscopy video is the substrate. We capture more of it, from more procedures, than anyone else. The archive grows every day.

One model base. Built for the full procedure.

EndoDINO

EndoML

See the full evidence package.

Infrastructure for the future of endoscopy AI.

The most powerful AI for endoscopy.
Trained on the largest dataset.

Many of the most impactful human diseases
are mediated by the gut.

State-of-the-art on GI benchmarks.
Validated across sites, scopes, and patient populations.